Part 1 – An Overview of Neuroendocrine Cancer

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Disclaimer: Some stock video has been used throughout the presentation of this course. This should not be taken as instructional medical practice.

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1.1.1 Neuroendocrine Cells and their Function

1.1.2 Examples of Neuroendocrine Cells and their Functions

1.1.3 The Importance of Terminology

1.1.4 Neuroendocrine Tumours

1.1.5 The Epidemiology of Neuroendocrine Tumours

REFLECTIVE POINT – CANCER RATES & DIAGNOSIS

1.1.6 Risk Factors for Neuroendocrine Cancers

1.1.7 Inherited Family Syndromes and Increased Neuroendocrine Cancer Risk

1.1.8 Modifiable Cancer Risks

1.1.9 Classification of Neuroendocrine Cancer

1.1.10 Neuroendocrine Cancers are Heterogenous

1.1.11 Site of Origin

1.1.12 Classification of Gastroenteropancreatic Neuroendocrine Cancer (GEP-NETs) by Site

1.1.13 Histology & Grading of Neuroendocrine Cancer

1.1.14 WHO (2022) Grading System for Neuroendocrine Cancer

1.1.15 WHO (2022) Grading System for Lung Neuroendocrine Cancer

1.1.16 Staging and the TNM System

1.1.17 Functioning / Non-Functioning Neuroendocrine Cancer

1.1.18 Neuroendocrine Cancer Survival

1.1.19 Median Overall Survival

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1.2.1 Presenting Signs & Symptoms

1.2.2 Delays in Diagnosis

1.2.3 Presenting Features of Neuroendocrine Cancer of the Small Intestine

1.2.4 Carcinoid Syndrome and Carcinoid Related Diarrhoea

1.2.5 Presenting Symptoms of Pancreatic & Lung Neuroendocrine Cancer

REFLECTIVE POINT – DELAYS IN DIAGNOSIS

1.2.6 Pathways to Diagnosis and Staging

1.2.7 Laboratory Tests

1.2.8 Imaging and Somatostatin Receptors in Neuroendocrine Cancer

1.2.9 Somatostatin Receptor Imaging

1.2.10 Further Tests

Interview with a Patient (TBC)

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1.3.1 Treatment Decision-Making for Neuroendocrine Cancer

1.3.2 The Role of Surgery in Neuroendocrine Cancer

1.3.3 Small Intestinal Neuroendocrine Cancer: The Role of Bowel Surgery

1.3.4 Treatment Planning for Small Intestinal Neuroendocrine Cancer

REFLECTIVE POINT – CATHY

1.3.5 Pancreatic Neuroendocrine Cancer: Primary Surgery

1.3.6 Debulking Surgery to the Liver

1.3.7 Control of Tumour Growth

1.3.8 Liver-Directed Therapies

1.3.9 Liver-Directed Therapies – Type and Use in Practice

1.3.10 Systemic Therapies

1.3.11 Somatostatin Analogues

1.3.12 Molecular Targeted Therapies

1.3.13 Cytotoxic Chemotherapy

1.3.14 Peptide Receptor Radionuclide Therapy (PRRT)

1.3.15 Radiation Protection

1.3.16 Issues in Treating Neuroendocrine Cancer Patients

1.3.17 An Ideal Patient Care Pathway for Neuroendocrine Cancer

1.3.18 Treatment Planning Summary

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1.4.1 Essential Information for Shared Decision Making

REFLECTIVE POINT – SADIQ

1.4.2 The Challenges of Neuroendocrine Cancer & the Role of the Specialist Nurse

1.4.3 Health Related Quality of Life (HRQoL)

1.4.4 Gastrointestinal Symptoms and Neuroendocrine Cancer

GI Doctor / Consultant Interview Slide 83

REFLECTIVE POINT – JACOB

1.4.5 Small Intestinal Bacterial Overgrowth (SIBO)

1.4.6 Bile Acid Malabsorption (BAM)

REFLECTIVE POINT – CARRIE

1.4.7 Exocrine Pancreatic Insufficiency (EPI)

REFLECTIVE POINT – KASIM

1.4.8 Nursing Care of Patients with Gastrointestinal Symptoms